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Dxo1 is a novel eukaryotic enzyme with both decapping and 5′-3′ exoribonuclease activity

Recent studies showed that Rai1 is a crucial component of the mRNA 5′-end capping quality control mechanism in yeast. The yeast genome encodes a weak homolog of Rai1, Ydr370C, but little is known about this protein. Here we report the crystal structures of Kluyveromyces lactis Ydr370C and the first...

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Bibliografiske detaljer
Main Authors: Chang, Jeong Ho, Jiao, Xinfu, Chiba, Kunitoshi, Oh, ChanSeok, Martin, Charles E., Kiledjian, Megerditch, Tong, Liang
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711404/
https://ncbi.nlm.nih.gov/pubmed/22961381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2381
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