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NMR and molecular modelling studies on the interaction of fluconazole with β-cyclodextrin

BACKGROUND: Fluconazole (FLZ) is a synthetic, bistriazole antifungal agent, effective in treating superficial and systemic infections caused by Candida species. Major challenges in formulating this drug for clinical applications include solubility enhancement and improving stability in biological sy...

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Autors principals: Upadhyay, Santosh Kumar, Kumar, Gyanendra
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739844/
https://ncbi.nlm.nih.gov/pubmed/19664263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-3-9
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