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NMR and molecular modelling studies on the interaction of fluconazole with β-cyclodextrin

BACKGROUND: Fluconazole (FLZ) is a synthetic, bistriazole antifungal agent, effective in treating superficial and systemic infections caused by Candida species. Major challenges in formulating this drug for clinical applications include solubility enhancement and improving stability in biological sy...

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Detalhes bibliográficos
Main Authors: Upadhyay, Santosh Kumar, Kumar, Gyanendra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739844/
https://ncbi.nlm.nih.gov/pubmed/19664263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-3-9
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