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β-cyclodextrin complexes of celecoxib: Molecular-modeling, characterization, and dissolution studies
Celecoxib, a specific inhibitor of cycloxygenase-2 (COX-2) is a poorly water-soluble nonsteroidal anti-inflammatory drug with relatively low bioavailability. The effect of β-cyclodextrin on the aqueous solubility and dissolution rate of celecoxib was investigated. The possibility of molecular arrang...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer New York
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750942/ https://ncbi.nlm.nih.gov/pubmed/15198508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps060107 |
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