Загрузка...
Pseudo-hyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization
The microtubule-associated protein tau, in a hyperphosphorylated form, aggregates into insoluble paired-helical filaments (PHFs) in Alzheimer’s disease (AD) and other tauopathies. In AD, there are approximately 8 mol of phosphate per mol of tau distributed among approximately 30 PHF phosphorylation...
Сохранить в:
| Главные авторы: | , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739831/ https://ncbi.nlm.nih.gov/pubmed/19459590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900602h |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|