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Mechanical stretch decreases FAK phosphorylation and reduces cell migration through loss of JIP3-induced JNK phosphorylation in airway epithelial cells

JNK is a nonreceptor kinase involved in the early events that signal cell migration after injury. However, the linkage to early signals required to initiate the migration response to JNK has not been defined in airway epithelial cells, which exist in an environment subjected to cyclic mechanical str...

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Main Authors: Desai, Leena P., White, Steven R., Waters, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739770/
https://ncbi.nlm.nih.gov/pubmed/19574423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00076.2009
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