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A novel direct homogeneous assay for ATP citrate lyase

ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg(2+) as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acid...

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Bibliografiske detaljer
Main Authors: Ma, Zhengping, Chu, Ching-Hsuen, Cheng, Dong
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739766/
https://ncbi.nlm.nih.gov/pubmed/19286649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D900008-JLR200
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