Cargando...
Host-deficiency in Vav 2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo
Vav guanine nucleotide exchange factors (GEFs) modulate changes in cytoskeletal organization through activation of Rho, Rac, and Cdc42 small GTPases. While Vav1 expression is restricted to the immune system, Vav2 and 3 are expressed in several tissues, including highly vascularized organs. Here, we...
Gardado en:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739740/ https://ncbi.nlm.nih.gov/pubmed/19435813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0401 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|