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The first total synthesis of (±)-4-methoxydecanoic acid: a novel antifungal fatty acid
The hitherto unknown (±)-4-methoxydecanoic acid was synthesized in six steps and in 25% overall yield starting from commercially available 4-penten-1-ol. The title compound demonstrated seventeen fold higher antifungal activity (MIC = 1.5 mM) against Candida albicans ATCC 60193 and Cryptococcus. neo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739663/ https://ncbi.nlm.nih.gov/pubmed/20161109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.07.074 |
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