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Functional Link between DNA Damage Responses and Transcriptional Regulation by ATM in Response to a Histone Deacetylase Inhibitor TSA

PURPOSE: Mutations in the ATM (ataxia-telangiectasia mutated) gene, which encodes a 370 kd protein with a kinase catalytic domain, predisposes people to cancers, and these mutations are also linked to ataxia-telangiectasia (A-T). The histone acetylaion/deacetylation- dependent chromatin remodeling c...

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Bibliografski detalji
Glavni autor: Lee, Jong-Soo
Format: Artigo
Jezik:Inglês
Izdano: Korean Cancer Association 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739330/
https://ncbi.nlm.nih.gov/pubmed/19746225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2007.39.3.116
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