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Functional Link between DNA Damage Responses and Transcriptional Regulation by ATM in Response to a Histone Deacetylase Inhibitor TSA
PURPOSE: Mutations in the ATM (ataxia-telangiectasia mutated) gene, which encodes a 370 kd protein with a kinase catalytic domain, predisposes people to cancers, and these mutations are also linked to ataxia-telangiectasia (A-T). The histone acetylaion/deacetylation- dependent chromatin remodeling c...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Cancer Association
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739330/ https://ncbi.nlm.nih.gov/pubmed/19746225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2007.39.3.116 |
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