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Distributive and Directional Behavior of Lantibiotic Synthetases Revealed by High-Resolution Tandem Mass Spectrometry

[Image: see text] The lantibiotic synthetases LctM and HalM2 are bifunctional enzymes that catalyze both the dehydration of serine and threonine residues and the Michael-type additions of cysteine residues to the resulting dehydroamino acids in their substrate peptides. Using Fourier transform mass...

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Detalhes bibliográficos
Main Authors: Lee, M. Violet, Ihnken, Leigh Anne Furgerson, You, Young Ok, McClerren, Amanda L., Donk, Wilfred A. van der, Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2009
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738757/
https://ncbi.nlm.nih.gov/pubmed/19663480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9033507
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