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Structure-Activity Relationship Studies of the Two-Component Lantibiotic Haloduracin

The lantibiotic haloduracin consists of two post-translationally processed peptides, Halα and Halβ, that act in synergy to provide bactericidal activity. An in vitro haloduracin production system was utilized to examine the biological impact of disrupting individual thioether rings in each peptide....

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Bibliografiske detaljer
Main Authors: Cooper, Lisa E., McClerren, Amanda L, Chary, Anita, van der Donk, Wilfred A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633096/
https://ncbi.nlm.nih.gov/pubmed/18940665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.07.020
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