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UTILIZATION OF SYNTHETIC PEPTIDES TO EVALUATE THE IMPORTANCE OF SUBSTRATE INTERACTION AT THE PROTEOLYTIC SITE OF ESCHERICHIA COLI LON PROTEASE

Lon, also known as protease La, is an ATP-dependent protease functioning to degrade many unstructured proteins. Currently, very little is known about the substrate determinants of Lon at the proteolytic site. Using synthetic peptides constituting different regions of the endogenous protein substrate...

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Bibliographic Details
Main Authors: Patterson-Ward, Jessica, Tedesco, Johnathan, Hudak, Jason, Fishovitz, Jennifer, Becker, James, Frase, Hilary, McNamara, Kirsten, Lee, Irene
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738752/
https://ncbi.nlm.nih.gov/pubmed/19285157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.02.015
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