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Active-site directed chemical tools for profiling mitochondrial Lon protease
Lon and ClpXP are the only soluble ATP-dependent proteases within the mammalian mitochondria matrix, which function in protein quality control by selectively degrading misfolded, misassembled or damaged proteins. Chemical tools to study these proteases in biological samples have not been identified,...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158820/ https://ncbi.nlm.nih.gov/pubmed/21520912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100408w |
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