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Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates
Lon, also known as the protease La, is a homo-oligomeric ATP-dependent protease, which is highly conserved in archaea, eubacteria and eukaryotic mitochondria and peroxisomes. Since its discovery, studies have shown that Lon activity is essential for cellular homeostasis, mediating protein quality co...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443057/ https://ncbi.nlm.nih.gov/pubmed/18359303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.02.010 |
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