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Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates

Lon, also known as the protease La, is a homo-oligomeric ATP-dependent protease, which is highly conserved in archaea, eubacteria and eukaryotic mitochondria and peroxisomes. Since its discovery, studies have shown that Lon activity is essential for cellular homeostasis, mediating protein quality co...

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Bibliografiske detaljer
Main Authors: Lee, Irene, Suzuki, Carolyn K
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443057/
https://ncbi.nlm.nih.gov/pubmed/18359303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.02.010
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