Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy without intrathecal prophylaxis

BACKGROUND: The prevalence of and risk factors for central nervous system recurrence in patients with acute promyelocytic leukemia are not well established and remain a controversial matter. DESIGN AND METHODS: Between 1996 and 2005, 739 patients with newly diagnosed acute promyelocytic leukemia enr...

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Main Authors: Montesinos, Pau, Díaz-Mediavilla, Joaquín, Debén, Guillermo, Prates, Virginia, Tormo, Mar, Rubio, Vicente, Pérez, Inmaculada, Fernández, Isolda, Viguria, Maricruz, Rayón, Chelo, González, José, de la Serna, Javier, Esteve, Jordi, Bergua, Juan M., Rivas, Concha, González, Marcos, González, Jose D., Negri, Silvia, Brunet, Salut, Lowenberg, Bob, Sanz, Miguel A.
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2009
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738716/
https://ncbi.nlm.nih.gov/pubmed/19608685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.007872
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