Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group

Few studies have examined the outcome of large numbers of patients with the microgranular variant (M3V) of acute promyelocytic leukemia (APL) in the all-trans retinoic acid era. Here, the outcome of 155 patients treated with all-trans retinoic acid–based therapy on 3 clinical trials, North American...

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Autori principali: Tallman, Martin S., Kim, Haesook T., Montesinos, Pau, Appelbaum, Frederick R., de la Serna, Javier, Bennett, John M., Deben, Guillermo, Bloomfield, Clara D., Gonzalez, Jose, Feusner, James H., Gonzalez, Marcos, Gallagher, Robert, Miguel, Jose D. Gonzalez-San, Larson, Richard A., Milone, Gustavo, Paietta, Elisabeth, Rayon, Chelo, Rowe, Jacob M., Rivas, Concha, Schiffer, Charles A., Vellenga, Edo, Shepherd, Lois, Slack, James L., Wiernik, Peter H., Willman, Cheryl L., Sanz, Miguel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031411/
https://ncbi.nlm.nih.gov/pubmed/20858857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-288613
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