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Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer

BACKGROUND: The HIV-1 Env glycoprotein mediates virus entry by catalyzing direct fusion between the virion membrane and the target cell plasma membrane. Env is composed of two subunits: gp120, which binds to CD4 and the coreceptor, and gp41, which is triggered upon coreceptor binding to promote the...

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書誌詳細
主要な著者: Salzwedel, Karl, Berger, Edward A
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738651/
https://ncbi.nlm.nih.gov/pubmed/19671162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-75
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