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NMR Mapping and Functional Confirmation of the Collagen Binding Sites of MMP-2
Interactions of matrix metalloproteinase-2 (MMP-2)(1) with native and denatured forms of several types of collagen are mediated by the collagen-binding domain (CBD). CBD positions substrates relative to the catalytic site and is essential for their cleavage. Our previous studies identified an CBD bi...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738612/ https://ncbi.nlm.nih.gov/pubmed/19459623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900513h |
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