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NMR Mapping and Functional Confirmation of the Collagen Binding Sites of MMP-2

Interactions of matrix metalloproteinase-2 (MMP-2)(1) with native and denatured forms of several types of collagen are mediated by the collagen-binding domain (CBD). CBD positions substrates relative to the catalytic site and is essential for their cleavage. Our previous studies identified an CBD bi...

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Detalhes bibliográficos
Main Authors: Xu, Xiaoping, Mikhailova, Margarita, Ilangovan, Udayar, Chen, Zhihua, Yu, Agnes, Pal, Sanjay, Hinck, Andrew P., Steffensen, Bjorn
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738612/
https://ncbi.nlm.nih.gov/pubmed/19459623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900513h
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