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Simian Virus 40 T-Antigen-Mediated Gene Regulation in Enterocytes Is Controlled Primarily by the Rb-E2F Pathway

Simian virus 40 large T antigen (TAg) contributes to cell transformation, in part, by targeting two well-characterized tumor suppressors, pRb and p53. TAg expression affects the transcriptional circuits controlled by Rb and by p53. We have performed a microarray analysis to examine the global change...

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Detalhes bibliográficos
Main Authors: Rathi, Abhilasha V., Sáenz Robles, M. Teresa, Cantalupo, Paul G., Whitehead, Robert H., Pipas, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738269/
https://ncbi.nlm.nih.gov/pubmed/19570859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00583-09
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