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Is Single-Strand Conformation Polymorphism Analysis of the Full 5′ Untranslated Region an Adequate Approach To Study Hepatitis C Virus Quasispecies Distribution?

Single-strand conformation polymorphism (SSCP) analysis is used by many laboratories to study the quasispecies distribution of the hepatitis C virus (HCV). Here we question the validity of this experimental approach, as conclusions are drawn from the analysis of the migration patterns of two ssDNA m...

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Detalhes bibliográficos
Main Authors: Vera-Otarola, Jorge, Barría, María Inés, León, Ursula, Carvallo, Pilar, Soza, Alejandro, López-Lastra, Marcelo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738205/
https://ncbi.nlm.nih.gov/pubmed/19553315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00971-09
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