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A Strongly Transdominant Mutation in the Human Immunodeficiency Virus Type 1 gag Gene Defines an Achilles Heel in the Virus Life Cycle

The human immunodeficiency virus type 1 (HIV-1) protease (PR) makes five obligatory cleavages in the viral Gag polyprotein precursor. The cleavage events release the virion structural proteins from the precursor and allow the virion to undergo maturation to become infectious. The protease cleavage b...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lee, Sook-Kyung, Harris, Janera, Swanstrom, Ronald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738153/
https://ncbi.nlm.nih.gov/pubmed/19515760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00317-09
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