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Evolution of Human Immunodeficiency Virus Type 1 Protease Genotypes and Phenotypes In Vivo under Selective Pressure of the Protease Inhibitor Ritonavir

We examined the population dynamics of human immunodeficiency virus type 1 pro variants during the evolution of resistance to the protease inhibitor ritonavir (RTV) in vivo. pro variants were followed in subjects who had added RTV to their previously failed reverse transcriptase inhibitor therapy us...

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Detalhes bibliográficos
Main Authors: Resch, Wolfgang, Parkin, Neil, Watkins, Terri, Harris, Janera, Swanstrom, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182672/
https://ncbi.nlm.nih.gov/pubmed/16051856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10638-10649.2005
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