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Therapeutic Memory T Cells Require Costimulation for Effective Clearance of a Persistent Viral Infection

Persistent viral infections are a major health concern worldwide. During persistent infection, overwhelming viral replication and the rapid loss of antiviral T-cell function can prevent immune-mediated clearance of the infection, and therapies to reanimate the immune response and purge persistent vi...

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Main Authors: Garidou, Lucile, Heydari, Sara, Truong, Phi, Brooks, David G., McGavern, Dorian B.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738141/
https://ncbi.nlm.nih.gov/pubmed/19553326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00027-09
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