Role of Protein Tyrosine Phosphatase 1B in VEGF Signaling and Cell-Cell Adhesions in Endothelial Cells

Vascular endothelial growth factor (VEGF) binding induces phosphorylation of VEGF receptor-2 (VEGFR2) in tyrosine, which is followed by disruption of VE-cadherin-mediated cell-cell contacts of endothelial cells (ECs), thereby stimulating EC proliferation and migration to promote angiogenesis. Tyrosi...

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Detalhes bibliográficos
Main Authors: Nakamura, Yoshimasa, Patrushev, Nikolay, Inomata, Hyoe, Mehta, Dolly, Urao, Norifumi, Kim, Ha Won, Razvi, Masooma, Kini, Vidisha, Mahadev, Kalyankar, Goldstein, Barry J., Mckinney, Ronald, Fukai, Tohru, Ushio-Fukai, Masuko
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737681/
https://ncbi.nlm.nih.gov/pubmed/18451337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.167080
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