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Copper-Triggered Aggregation of Ubiquitin

Neurodegenerative disorders share common features comprising aggregation of misfolded proteins, failure of the ubiquitin-proteasome system, and increased levels of metal ions in the brain. Protein aggregates within affected cells often contain ubiquitin, however no report has focused on the aggregat...

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Detalles Bibliográficos
Main Authors: Arnesano, Fabio, Scintilla, Simone, Calò, Vincenza, Bonfrate, Elena, Ingrosso, Chiara, Losacco, Maurizio, Pellegrino, Teresa, Rizzarelli, Enrico, Natile, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737635/
https://ncbi.nlm.nih.gov/pubmed/19756145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007052
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