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DNA-Triggered Aggregation of Copper, Zinc Superoxide Dismutase in the Presence of Ascorbate

The oxidative damage hypothesis proposed for the function gain of copper, zinc superoxide dismutase (SOD1) maintains that both mutant and wild-type (WT) SOD1 catalyze reactions with abnormal substrates that damage cellular components critical for viability of the affected cells. However, whether the...

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Détails bibliographiques
Auteurs principaux: Yin, Jun, Hu, Si, Jiang, Wei, Liu, Liang, Lan, Shemin, Song, Xuegang, Liu, Changlin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924893/
https://ncbi.nlm.nih.gov/pubmed/20808835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012328
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