Kv1.3 gene-targeted deletion alters longevity and reduces adiposity by increasing locomotion and metabolism in melanocortin-4 receptor-null mice

OBJECTIVE: Gene-targeted deletion of the voltage-gated potassium channel, Kv1.3, results in ‘super-smeller’ mice that have altered firing patterns of mitral cells in the olfactory bulb, modified axonal targeting to glomerular synaptic units, and behaviorally have an increased ability to detect and d...

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Bibliographic Details
Main Authors: Tucker, K, Overton, JM, Fadool, DA
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737548/
https://ncbi.nlm.nih.gov/pubmed/18542083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2008.77
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