Kv1.3 Channel Gene-Targeted Deletion Produces “Super-Smeller Mice” with Altered Glomeruli, Interacting Scaffolding Proteins, and Biophysics

Mice with gene-targeted deletion of the Kv1.3 channel were generated to study its role in olfactory function. Potassium currents in olfactory bulb mitral cells from Kv1.3 null mice have slow inactivation kinetics, a modified voltage dependence, and a dampened C-type inactivation and fail to be modul...

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Auteurs principaux: Fadool, D.A., Tucker, K., Perkins, R., Fasciani, G., Thompson, R.N., Parsons, A.D., Overton, J.M., Koni, P.A., Flavell, R.A., Kaczmarek, L.K.
Format: Artigo
Langue:Inglês
Publié: 2004
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737549/
https://ncbi.nlm.nih.gov/pubmed/14766178
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