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Kv1.3 gene-targeted deletion alters longevity and reduces adiposity by increasing locomotion and metabolism in melanocortin-4 receptor-null mice
OBJECTIVE: Gene-targeted deletion of the voltage-gated potassium channel, Kv1.3, results in ‘super-smeller’ mice that have altered firing patterns of mitral cells in the olfactory bulb, modified axonal targeting to glomerular synaptic units, and behaviorally have an increased ability to detect and d...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737548/ https://ncbi.nlm.nih.gov/pubmed/18542083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2008.77 |
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