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Activation of the prostaglandin system in response to sleep loss in healthy humans: Potential mediator of increased spontaneous pain

Insufficient duration of sleep is a highly prevalent behavioral pattern in society that has been shown to cause an increase in spontaneous pain and sensitivity to noxious stimuli. Prostaglandins (PG), in particular PGE2, are key mediators of inflammation and pain, and we investigated whether PGE2 is...

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Autors principals: Haack, Monika, Lee, Erin, Cohen, Daniel, Mullington, Janet M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737342/
https://ncbi.nlm.nih.gov/pubmed/19560866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.05.029
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