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Activation of the prostaglandin system in response to sleep loss in healthy humans: Potential mediator of increased spontaneous pain

Insufficient duration of sleep is a highly prevalent behavioral pattern in society that has been shown to cause an increase in spontaneous pain and sensitivity to noxious stimuli. Prostaglandins (PG), in particular PGE2, are key mediators of inflammation and pain, and we investigated whether PGE2 is...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Haack, Monika, Lee, Erin, Cohen, Daniel, Mullington, Janet M.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737342/
https://ncbi.nlm.nih.gov/pubmed/19560866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.05.029
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