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A New Approach in the Preparation of Dendrimer-Based Bifunctional Diethylenetriaminepentaacetic Acid MR Contrast Agent Derivatives

In this paper we report a new method to prepare and characterize a contrast agent based on a fourth-generation (G4) polyamidoamine (PAMAM) dendrimer conjugated to the gadolinium complex of the bifunctional diethylenetriamine pentaacetic acid derivative (1B4M-DTPA). The method involves pre-forming th...

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Detalhes bibliográficos
Main Authors: Nwe, Kido, Xu, Heng, Regino, Celeste Aida S., Bernardo, Marcelino, Ileva, Lilia, Riffle, Lisa, Wong, Karen J., Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737254/
https://ncbi.nlm.nih.gov/pubmed/19555072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900057z
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