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Preparation, Characterization and In Vivo Assessment of Gd-Albumin and Gd-Dendrimer Conjugates as Intravascular Contrast-Enhancing Agents for MRI

We report in vivo and in vitro MRI properties of six gadolinium-dendrimer and gadolinium-albumin conjugates of derivatized acyclic diethylenetriamine-N,N’,N’,N’’, N’’-pentaacetic acid (1B4M) and macrocyclic 1,4,7,10-tetraazacyclododecane-N,N’,N’’,N’’’-tetraacetic acid (C-DOTA). The three albumin-bas...

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Detalhes bibliográficos
Main Authors: Nwe, Kido, Milenic, Diane, Bryant, L. Henry, Regino, Celeste A. S., Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081896/
https://ncbi.nlm.nih.gov/pubmed/21463567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2011.01.017
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