Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits

Modulation of voltage-gated potassium (K(V)) channels by the KCNE family of single transmembrane proteins has physiological and pathophysiological importance. All five KCNE proteins (KCNE1–KCNE5) have been demonstrated to modulate heterologously expressed KCNQ1 (K(V)7.1) with diverse effects, making...

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Detalhes bibliográficos
Main Authors: Vanoye, Carlos G., Welch, Richard C., Daniels, Melissa A., Manderfield, Lauren J., Tapper, Andrew R., Sanders, Charles R., George, Alfred L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737226/
https://ncbi.nlm.nih.gov/pubmed/19687231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910234
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