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Structure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel(,)
KCNE1 is a single span membrane protein that modulates the voltage-gated potassium channel KCNQ1 (K(V)7.1) by slowing activation and enhancing channel conductance to generate the slow delayed rectifier current (I(Ks)) that is critical for the repolarization phase of the cardiac action potential. Per...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580054/ https://ncbi.nlm.nih.gov/pubmed/18611041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800875q |
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