Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region

In addition to the degradation of homologous RNAs through the RNA interference (RNAi) pathway, small interfering RNAs (siRNAs) can in some systems induce cytosine methylation and transcriptional silencing of homologous promoters. Targeting of HIV-1 by RNAi results in transient suppression of the vir...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Suzuki, Kazuo, Shijuuku, Toshiaki, Fukamachi, Toshihiko, Zaunders, John, Guillemin, Gilles, Cooper, David, Kelleher, Anthony
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Library Publishing Media 2005
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737205/
https://ncbi.nlm.nih.gov/pubmed/19771207
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