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A role for CD47 in the development of experimental colitis mediated by SIRPα(+)CD103(−) dendritic cells

Mesenteric lymph node (mLN) CD103 (αE integrin)(+) dendritic cells (DCs) induce regulatory T cells and gut tolerance. However, the function of intestinal CD103(−) DCs remains to be clarified. CD47 is the ligand of signal regulatory protein α (SIRPα) and promotes SIRPα(+) myeloid cell migration. We f...

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Hlavní autoři: Fortin, Genevieve, Raymond, Marianne, Van, Vu Quang, Rubio, Manuel, Gautier, Patrick, Sarfati, Marika, Franchimont, Denis
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737153/
https://ncbi.nlm.nih.gov/pubmed/19703989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082805
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