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The CD47-SIRPα immune checkpoint
The cytotoxic activity of myeloid cells is regulated by a balance of signals that are transmitted through inhibitory and activating receptors. The Cluster of Differentiation 47 (CD47) protein, expressed on both healthy and cancer cells, plays a pivotal role in this balance by delivering a “don’t eat...
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| Publicado no: | Immunity |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7340539/ https://ncbi.nlm.nih.gov/pubmed/32433947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.04.011 |
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