CD47(Low) Status on CD4 Effectors Is Necessary for the Contraction/Resolution of the Immune Response in Humans and Mice

How do effector CD4 T cells escape cell death during the contraction of the immune response (IR) remain largely unknown. CD47, through interactions with thrombospondin-1 (TSP-1) and SIRP-α, is implicated in cell death and phagocytosis of malignant cells. Here, we reported a reduction in SIRP-α-Fc bi...

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Main Authors: Van, Vu Quang, Baba, Nobuyasu, Rubio, Manuel, Wakahara, Keiko, Panzini, Benoit, Richard, Carole, Soucy, Genevieve, Franchimont, Denis, Fortin, Genevieve, Torres, Ana Carolina Martinez, Cabon, Lauriane, Susin, Santos, Sarfati, Marika
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411572/
https://ncbi.nlm.nih.gov/pubmed/22870271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041972
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