Gene Expression Signatures Predictive of Early Response and Outcome in High-Risk Childhood Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

PURPOSE: To identify children with acute lymphoblastic leukemia (ALL) at initial diagnosis who are at risk for inferior response to therapy by using molecular signatures. PATIENTS AND METHODS: Gene expression profiles were generated from bone marrow blasts at initial diagnosis from a cohort of 99 ch...

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Main Authors: Bhojwani, Deepa, Kang, Huining, Menezes, Renee X., Yang, Wenjian, Sather, Harland, Moskowitz, Naomi P., Min, Dong-Joon, Potter, Jeffrey W., Harvey, Richard, Hunger, Stephen P., Seibel, Nita, Raetz, Elizabeth A., Pieters, Rob, Horstmann, Martin A., Relling, Mary V., den Boer, Monique L., Willman, Cheryl L., Carroll, William L.
Format: Artigo
Language:Inglês
Published: American Society of Clinical Oncology 2008
Subjects:
Pediatric Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736991/
https://ncbi.nlm.nih.gov/pubmed/18802149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.14.4519
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