Gene Expression Signatures Predictive of Early Response and Outcome in High-Risk Childhood Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

PURPOSE: To identify children with acute lymphoblastic leukemia (ALL) at initial diagnosis who are at risk for inferior response to therapy by using molecular signatures. PATIENTS AND METHODS: Gene expression profiles were generated from bone marrow blasts at initial diagnosis from a cohort of 99 ch...

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Detalhes bibliográficos
Main Authors: Bhojwani, Deepa, Kang, Huining, Menezes, Renee X., Yang, Wenjian, Sather, Harland, Moskowitz, Naomi P., Min, Dong-Joon, Potter, Jeffrey W., Harvey, Richard, Hunger, Stephen P., Seibel, Nita, Raetz, Elizabeth A., Pieters, Rob, Horstmann, Martin A., Relling, Mary V., den Boer, Monique L., Willman, Cheryl L., Carroll, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2008
Assuntos:
Pediatric Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736991/
https://ncbi.nlm.nih.gov/pubmed/18802149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.14.4519
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