Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

The underlying pathways that lead to relapse in childhood acute lymphoblastic leukemia (ALL) are unknown. To comprehensively characterize the molecular evolution of relapsed childhood B-precursor ALL, we used human 500K single-nucleotide polymorphism arrays to identify somatic copy number alteration...

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Detalhes bibliográficos
Main Authors: Yang, Jun J., Bhojwani, Deepa, Yang, Wenjian, Cai, Xiangjun, Stocco, Gabriele, Crews, Kristine, Wang, Jinhua, Morrison, Debra, Devidas, Meenakshi, Hunger, Stephen P., Willman, Cheryl L., Raetz, Elizabeth A., Pui, Ching-hon, Evans, William E., Relling, Mary V., Carroll, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581992/
https://ncbi.nlm.nih.gov/pubmed/18768390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-165027
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