Rapid detection of the CYP2A6*12 hybrid allele by Pyrosequencing(® )technology

BACKGROUND: Identification of CYP2A6 alleles associated with reduced enzyme activity is important in the study of inter-individual differences in drug metabolism. CYP2A6*12 is a hybrid allele that results from unequal crossover between CYP2A6 and CYP2A7 genes. The 5' regulatory region and exons...

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Detaylı Bibliyografya
Asıl Yazarlar: Koontz, Deborah A, Huckins, Jacqueline J, Spencer, Antonina, Gallagher, Margaret L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2009
Konular:
Technical Advance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736934/
https://ncbi.nlm.nih.gov/pubmed/19703308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-80
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