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Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma
BACKGROUND: Recently, oncogenic G protein alpha subunit q (GNAQ) mutations have been described in about 50% of uveal melanomas and in the blue nevi of the skin. METHODS: GNAQ exon 5 was amplified from 75 ciliary body and choroidal melanoma DNAs and sequenced directly. GNAQ mutation status was correl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736834/ https://ncbi.nlm.nih.gov/pubmed/19654573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605226 |
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