β-Catenin Promotes Survival of Renal Epithelial Cells by Inhibiting Bax

Ischemia activates Bax, a proapoptotic BCL2 protein, as well as the prosurvival β-catenin/Wnt signaling pathway. To test the hypothesis that β-catenin/Wnt signaling regulates Bax-mediated apoptosis after induction of metabolic stress, which occurs during renal ischemia, we infected immortalized and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Zhiyong, Havasi, Andrea, Gall, Jonathan M., Mao, Haiping, Schwartz, John H., Borkan, Steven C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2009
Pynciau:
Basic Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736777/
https://ncbi.nlm.nih.gov/pubmed/19696224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009030253
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