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β-Catenin Promotes Survival of Renal Epithelial Cells by Inhibiting Bax
Ischemia activates Bax, a proapoptotic BCL2 protein, as well as the prosurvival β-catenin/Wnt signaling pathway. To test the hypothesis that β-catenin/Wnt signaling regulates Bax-mediated apoptosis after induction of metabolic stress, which occurs during renal ischemia, we infected immortalized and...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736777/ https://ncbi.nlm.nih.gov/pubmed/19696224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009030253 |
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