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Renal FcRn Reclaims Albumin but Facilitates Elimination of IgG

The widely distributed neonatal Fc receptor (FcRn) contributes to maintaining serum levels of albumin and IgG in adults. In the kidney, FcRn is expressed on the podocytes and the brush border of the proximal tubular epithelium. Here, we evaluated the role of renal FcRn in albumin and IgG metabolism....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sarav, Menaka, Wang, Ying, Hack, Bradley K., Chang, Anthony, Jensen, Mark, Bao, Lihua, Quigg, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736763/
https://ncbi.nlm.nih.gov/pubmed/19661163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008090976
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