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Residues Leu261, Trp264, and Phe265 Account for Apolipoprotein E-Induced Dyslipidemia and Affect the Formation of Apolipoprotein E-Containing High-Density Lipoprotein
Overexpression of apolipoprotein E (apoE) induces hypertriglyceridemia in apoE-deficient mice, which is abrogated by deletion of the carboxy-terminal segment of residues 260–299. We have used adenovirus-mediated gene transfer in apoE(−/−) and apoA-I(−/−) mice to test the effect of three sets of apoE...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736595/ https://ncbi.nlm.nih.gov/pubmed/17655277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700232g |
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